ea0063ep125 | Reproductive Endocrinology | ECE2019
Chaves Catarina
, Cunha Filipe
, Rangel Ricardo
, Coelho Daniela
, Vieira Margarida
, Garrido Susana
, Martinho Mariana
, Almeida Margarida
Introduction: Klinefelter syndrome (KS) represents the most common cause of hypergonadotrophic hypogonadism, with an estimated prevalence of 1:500 to 1:1000 men. This syndrome is characterized by the presence of an additional X chromosome. Eighty percent present with a 47,XXY karyotype and the remaining 20% present with a 47,XXY/46,XY mosaic or with multiple X chromosome aneuploidies, often with additional Y chromosomes. The presence of a 47,XXY/46,XX mosaic with male phenotyp...